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An increased serum level of which of the following analytes is most commonly associated with decreased glomerular filtration

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What endogenous substance may cause a positive interference in the urease/glutamate dehydrogenase assay? Urea is hydrolyzed in the presence of water and urease to form ammonia and CO2. Under the catalytic action of GLDH, ammonia reacts with a-oxoglutaric acid and NADH2, whereby glutamic acid and NAD are formed.

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